Core Director: Howard Kipen, MD, MPH
Core Co-Director: Judith Graber, PhD
Members: Kathy Black, PhD, MPH, Debra Laskin, PhD, Pamela A. Ohman-Strickland, Ph.D.
The mission of CEED is to improve human health by performing translational research using emerging science, engineering, and technology to determine how the environment, genome and epigenome interact to modulate the risk of adverse health outcomes.
The Integrative Health Sciences Facility Core (IHSFC) plays a central role in achieving the research mission of the CEED. The IHSFC is the nexus for the Center’s interdisciplinary and translational research mission. Its goal is to advance the integration of basic, translational, clinical, and epidemiological research. The IHSFC facilitates dialog among CEED members from different disciplines and provides guidance and training in design and implementation of studies in population (observational) and clinical epidemiology providing expertise in a wide range of methodologies including controlled exposure, survey research, controlled trials, and clinical panel studies. IHSFC faculty and staff provide technical assistance with study design, subject recruitment, screening, management, and retention, questionnaire design, IRB application, clinical procedures, and collection and processing of human samples for cellular, pathological and molecular analyses. As such the IHSFC plays a key role in training and faculty development. The IHSFC maintains the Center’s Sample Management System (SMS), which integrates biological sample management and analysis by Facility Cores.
The IHSFC is also the portal for biostatistics, data management, archiving and security, and facilitates bidirectional translation of clinical and animal studies. Furthermore, IHSFC activities, particularly recruitment, dovetail to mutual advantage, and with overlapping faculty and staff (K. Black, H. Kipen, R. Laumbach, J. Graber) in our Community Engagement Core (CEC).
The IHSFC leadership has expertise in clinical research and environmental/occupational epidemiology: